科研情况 |
代表性科研成果： [1] Ziru Sun, Jianbin Han, Jun Xu, Weijie Song, Yujun Cui, Yang Liu, Liu Yang, Xiaoqi Meng, Jie Huang, Shengnan Liu,* Qingzhi Gao.* Discovery of the Next-Generation Platinum-Based Anticancer Agents for Combating Oxaliplatin-Induced Drug Resistance. Journal of Medicinal Chemistry 2024, 67, 10190-10210. [2] Shengnan Liu,† Ziru Sun,† Min Liang, Weijie Song, Ru Zhang, Yunli Shi, Yujun Cui, Qingzhi Gao.* An Unrevealed Molecular Function of Corannulene Buckybowl Glycoconjugates in Selective Tumor Annihilation by Targeting the Cancer-Specific Warburg Effect. Advanced Science 2022, 9, 2105315. [3] Yaru Li,† Ziru Sun,† Yujun Cui, Heming Zhang, Shunjie Zhang, Xinyu Wang, Shengnan Liu,* Qingzhi Gao.* Oxaliplatin derived monofunctional triazole-containing platinum (II) complex counteracts oxaliplatin-induced drug resistance in colorectal cancer. Bioorganic chemistry 2021, 107, 104636. [4]张儒,孙子茹,刘胜男,高清志.新型冠状病毒治疗药物的研究现状及展望[J].科学通报2022, 67, 933-947. [5]孙子茹,刘胜男,高清志.靶向葡萄糖转运蛋白(GLUTs)抗癌药物的开发[J].化学进展2020, 32(12), 1869-1878. [6] Shengnan Liu, WeijieSong, Yujun Cui, Ziru Sun, Zhenhua Huang, and Qingzhi Gao.* A GLUT1 inhibitor-based probe significantly ameliorates the sensitivity of tumor detection and diagnostic imaging. Chemical Communications 2021, 57, 5530-5533. [7]高清志,刘胜男,孙子茹.取代3-氟苯丙酸酯类化合物及其制备方法、药物组合及用途[P].CN117843589A. [8]高清志,刘胜男,孙子茹.用于治疗奥沙利铂耐药肿瘤的化合物、其制备方法、组合物及其用途[P].WO2025130985A1. |
