专业:生物学 研究方向:生物化学与分子生物学、计算机辅助药物设计 主持项目: (1)国家级人才项目--环境科学与技术(2014.06-2018.06) (2)山东省自然科学基金面上--含氯离去基团Pt(IV)抗肿瘤复合物与生物分子相互作用理论研究(2019.7-2022.6) (3)山东省教育基金--高端人才团队建设费(2018.4-2023.3) (4)中科院人才专项--稀土贵金属催化剂用于汽车尾气氮氧化物净化的计算机模拟研究 (2015.01-2018.06) (5)新疆维吾尔自治区自然科学基金--新疆稀土矿应用于机动车尾气净化的计算机模拟研究(2017.1-2018.07) (6)浙江省自然科学基金--稀土钙钛矿型氧化物用于汽车尾气催化净化的计算机模拟研究(2009.01-2010.12) 代表性论文: (1)Yingying Jiang,Hongwei Gao*,Pharmacophore-based drug design for the identification of novel butyrylcholinesterase inhibitors against Alzheimer's disease,Phytomedicine,2019,54, 278-290. (2)Yingni Sun*†, Lisheng Liang†, Meili Dong, Cong Li, Zhenzhen Liu andHongwei Gao*, Cofilin 2 in Serum as a Novel Biomarker for Alzheimer’s Disease in Han Chinese,Frontiers in Aging Neuroscience,2019, 00214: 1-11. (3)Hongwei Gao*,Predicting tyrosinase inhibition by 3D QSAR pharmacophore models and designing potential tyrosinase inhibitors from Traditional Chinese Medicine Database,Phytomedicine,2018,38, 145-157. (4) Gulmira Turdu, Yingying Jiang, Madina Kabas,Azizullo Musoev,Hongwei Gao*, Dipeptidyl peptidase-IV inhibitors as anti-diabetic agents – A brief review,Future Medicinal Chemistry,2018,10(10): 1229-1239. (5)Yingying Jiang,Hongwei Gao*, Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database,Bioorganic Chemistry,2018,76, 400-414. (6)Yue Yang,Hongwei Gao*, Density functional theory study on the molecular structure and vibration spectra of fenbufen,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2013,101, 119-126. (7)Lekun Liu,Hongwei Gao*, Zhaozhe Cui, Molecular structure and vibrational spectra studies on antipyrine derivative, 4-(2,3,4-trihydroxybenzylideneamino) antipyrine,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2013,112, 191-197. (8)Yue Yang,Hongwei Gao*, Comparison of DFT methods for molecular structure and vibration spectra of ofloxacin calculations,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2012,85, 303-309. 获奖情况: (1)浙江省高等学校科研成果奖,二等奖,1/5(排名),(2010.12) 荣誉称号: (1)国家级特聘专家, 1/1(排名),(2014.7) (2)浙江省“新世纪151人才工程”, 1/1(排名),(2009.8) (3)温州市“新世纪551人才工程” , 1/1(排名),(2010.11) (4)温州市优秀科技特派员, 1/1(排名),(2011.2) (5)温州医科大学第二批校级中青年学科带头人, 1/1(排名),(2010.10) (6)鲁东大学高层次A类人才,1/1(排名),(2018.9) |